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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATXN3
All Species:
29.09
Human Site:
Y288
Identified Species:
49.23
UniProt:
P54252
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54252
NP_001121168.1
364
41781
Y288
L
R
K
R
R
E
A
Y
F
E
K
Q
Q
Q
K
Chimpanzee
Pan troglodytes
XP_001146724
368
42242
Y288
L
R
K
R
R
E
A
Y
F
E
K
Q
Q
Q
K
Rhesus Macaque
Macaca mulatta
XP_001116022
352
40079
Y280
L
R
K
R
R
E
A
Y
F
E
K
Q
Q
Q
Q
Dog
Lupus familis
XP_537352
301
34778
D244
R
Q
E
I
D
M
E
D
E
E
A
D
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVD2
355
40515
Y288
L
R
R
R
R
E
A
Y
F
E
K
Q
Q
Q
Q
Rat
Rattus norvegicus
O35815
355
40428
Y288
L
R
K
R
R
E
A
Y
F
E
K
Q
Q
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507271
358
40934
Y295
L
R
K
R
R
E
A
Y
F
E
K
Q
Q
Q
Q
Chicken
Gallus gallus
Q9W689
363
41590
Y300
L
R
R
R
R
Q
A
Y
F
E
K
Q
Q
Q
Q
Frog
Xenopus laevis
NP_001085659
316
35907
E251
T
E
Q
L
T
S
E
E
L
R
Q
K
R
Q
A
Zebra Danio
Brachydanio rerio
NP_957398
266
30028
G209
A
I
Q
M
S
M
Q
G
S
S
D
A
G
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623341
340
38556
K266
N
K
R
N
D
V
D
K
Y
L
K
L
S
L
D
Nematode Worm
Caenorhab. elegans
O17850
317
35845
E258
E
N
L
R
K
A
I
E
L
S
Q
A
P
G
P
Sea Urchin
Strong. purpuratus
XP_786733
388
42119
T320
T
P
S
E
V
P
S
T
S
K
E
E
E
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M391
280
30674
V223
N
K
R
S
N
D
N
V
N
Q
Q
R
R
N
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
88.7
79.1
N.A.
80.2
80.4
N.A.
78
70.5
52.2
50.5
N.A.
N.A.
42.8
31.3
38.4
Protein Similarity:
100
97.8
90.1
80.7
N.A.
85.4
85.7
N.A.
85.1
79.9
64.8
61.8
N.A.
N.A.
59.6
48.6
56.4
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
86.6
N.A.
93.3
80
6.6
0
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
100
100
33.3
N.A.
100
93.3
N.A.
100
100
33.3
6.6
N.A.
N.A.
26.6
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
50
0
0
0
8
15
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
8
8
8
0
0
8
8
0
0
8
% D
% Glu:
8
8
8
8
0
43
15
15
8
58
8
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
36
0
8
0
0
8
0
8
58
8
0
8
15
% K
% Leu:
50
0
8
8
0
0
0
0
15
8
0
8
8
8
0
% L
% Met:
0
0
0
8
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
8
0
8
8
0
8
0
8
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
8
% P
% Gln:
0
8
15
0
0
8
8
0
0
8
22
50
50
50
43
% Q
% Arg:
8
50
29
58
50
0
0
0
0
8
0
8
15
8
15
% R
% Ser:
0
0
8
8
8
8
8
0
15
15
0
0
8
8
8
% S
% Thr:
15
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _